Can you die of a broken heart? Kardia is the story of Hope (Mimi Kuzyk) a pathologist who embarks on an unusual journey of reconciliation. Her story begins in the brief instant that her heart stops. With a photograph as her only artifact she sets out to unravel the mystery that surrounds her early life.
 
The film weaves together Hope’s present-day work in the science lab, with the bittersweet tale of her childhood. As a young girl (Ariel Waller) with a colourful imagination, Hope constructs an enchanting world for herself, her war pilot Dad (Peter Stebbings), and her Scottish caregiver Florrie (Donna Goodhand) – a world is that is much more bearable than the one she inhabits.
 
As an adult working in a modern-day laboratory, Hope explores the inner workings of the human heart, as well as its more mythical associations. The lab is also the place of a tenuous love story between two young people (Kristen Booth, Stephen Lobo) that Hope observes from a distance.
 
Hope discovers that the heart surgery she underwent as a child has inexplicably linked her life with another. With this understanding, she is finally able to reconcile what she believes, with the truth she learns.